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Dr. Kalpit H. Devani, MD, FACP, FACG, FASGE

Interventional Gastroenterologist | Clinical Innovator

Double-board-certified interventional gastroenterologist with director-level experience in building advanced endoscopy programs, therapeutic innovation, and expert consultation.

Dr. Kalpit Devani, MD, FACP, FACG, FASGE — interventional endoscopist in Greenville, South Carolina

Leading from the Front: In the Suite and at the System Level

Dr. Kalpit Devani started his medical training at Tianjin Medical University and completed his internal medicine residency and gastroenterology fellowship at Quillen College of Medicine, East Tennessee State University. He served as Lead Resident during residency and Chief Fellow during his GI fellowship. After fellowship, he continued to build his procedural skills through hands-on training, mentorship from senior interventional endoscopists, and direct case experience in complex hepatobiliary, pancreatic, and luminal disease.

His clinical work focuses on the cases that most gastroenterologists refer out. Therapeutic endoscopic ultrasound, complex ERCP in patients with surgically altered anatomy, endoscopic suturing for weight loss and post-bariatric revision, and incisionless repair of perforations and fistulas. Many of these procedures used to require open or laparoscopic surgery. Dr. Devani performs them through a flexible endoscope with no incisions, which means shorter recovery, fewer complications, and patients getting back to their lives sooner. He performs more than 1,000 advanced procedures each year and has built a high-volume endoscopy program that works closely with surgery, oncology, and hepatology.

Outside the procedure room, Dr. Devani has authored more than 30 peer-reviewed publications in journals including Gastroenterology, Cell Reports Medicine, and Alimentary Pharmacology and Therapeutics. He is invited faculty at national and international gastroenterology meetings, serves on committees with the American College of Gastroenterology and the American Society for Gastrointestinal Endoscopy, and reviews for major medical journals. His goal is to expand what is possible in interventional endoscopy and make that level of care accessible to more patients in his region.

Clinical & Procedural Expertise

Over 1,000 advanced procedures per year with minimally invasive, organ-sparing alternatives to surgery.

Endobariatrics & Metabolic Health

Endoscopic Sleeve Gastroplasty (ESG), Transoral Outlet Reduction (TORe), gastric sleeve revisions, and advanced endoscopic suturing for incisionless weight loss and post-surgical repair.

Diagnostic and Therapeutic EUS

Full-spectrum diagnostic and therapeutic EUS, including LAMS placement, EUS-GBD, targeted FNB, and EUS-guided liver biopsy.

Complex ERCP and ERCP in Altered Anatomy

The regional resource for difficult biliary access, including EDGE and GATE procedures for surgically altered anatomy, failed prior ERCPs, and emergency interventions.

Complex Luminal Endoscopy & Repair

EMR, advanced suturing for perforation closure, fistula management, and repair of gastrointestinal defects, bridging endoscopy and surgery.

Distinctions & Professional Fellowships

Recognized by peers for significant contributions to the field, Dr. Devani holds Fellowship status in the nation's most prestigious medical societies

American College of Physicians logo
FACP

American College of Physicians

American College of Gastroenterology logo
FACG

American College of Gastroenterology

American Society for Gastrointestinal Endoscopy logo
FASGE

American Society for Gastrointestinal Endoscopy

Selected Honors & Roles

National recognition for clinical innovation, research, and leadership

Early Career Leadership Program

American College of Gastroenterology (2025)

Editorial Board Member

ACG Case Reports Journal

Committee Service

ASGE DDW Video Plenary & World Cup Committee; ACG Minority Affairs & Cultural Diversity Committee

Fellow in Training Award

American College of Gastroenterology (2018)

Presidential Poster Awards

American College of Gastroenterology (2016, 2018)

Early Career Investigator Award

AGA, Digestive Disease Week (2017)

Best Reviewer

Annals of Internal Medicine, American College of Physicians (2019)

Research & Publications

30+ peer-reviewed publications and 75+ national and international presentations.

Published in journals including Gastroenterology, Cell Reports Medicine, Alimentary Pharmacology & Therapeutics, American Journal of Medicine, and Journal of Obesity.

View Full Publication List →
"My goal has always been to push the boundaries of what endoscopy can achieve: building programs that expand access, collaborating with industry to advance the tools we use, and ensuring that every patient benefits from the highest standard of evidence-based, minimally invasive care."

- Dr. Kalpit H. Devani

Education & Board Certifications

Fellowship

Gastroenterology (Chief Fellow): Quillen College of Medicine, East Tennessee State University

Residency

Internal Medicine (Lead Resident): Quillen College of Medicine, East Tennessee State University

Medical Education

MBBS: Tianjin Medical University, China

Board Certifications

ABIM Board Certified in Gastroenterology | ABIM Board Certified in Internal Medicine

Conditions Treated

Dr. Devani evaluates and manages a wide range of digestive and hepatobiliary conditions.

Abdominal PainAcid Reflux Disease (GERD)Barrett's EsophagusBile Duct StonesBile Duct StricturesBile Duct TumorsBiliary LeaksCeliac DiseaseCholangitisChronic PancreatitisColon CancerColon PolypsConstipationDiarrheaDilated Gastrojejunal AnastomosisDiverticulosis / DiverticulitisDysphagia (Swallowing Difficulty)Early Esophageal CancerEsophageal StricturesFatty Liver Disease (NAFLD/NASH)GallstonesGastroparesisGI Bleeding / Rectal BleedingGI FistulasHeartburnHelicobacter Pylori / Peptic Ulcer DiseaseHemorrhoidsHepatitisHiatal HerniaInflammatory Bowel Disease (Crohn's Disease & Ulcerative Colitis)Iron Deficiency AnemiaIrritable Bowel Syndrome (IBS)JaundiceLiver CirrhosisMetabolic SyndromeNausea and VomitingObesity / Weight ManagementPancreatic CancerPancreatic CystsPancreatic Fluid CollectionsPancreatitis (Acute and Chronic)Rectal CancerSubmucosal Tumors (GISTs)Walled-Off Pancreatic NecrosisWeight Regain After Bariatric Surgery

Procedures Performed

Advanced diagnostic and therapeutic procedures with a focus on minimally invasive, incisionless techniques.

Let's Connect

Whether you are a healthcare organization seeking advanced endoscopy leadership, an attorney in need of expert consultation, an industry partner exploring clinical collaboration, or a physician with a complex referral, Dr. Devani is available and ready to engage.